Skip to content
Word ChallengeWord Challenge

Lupus

5 lettersnoun

Updated June 2026

Definition

a chronic autoimmune disease; also Latin for wolf

The lupus diagnosis required long-term treatment.

Pronunciation

Syllables

lu·pus

Word Game Tips

🟩

Wordle

"Lupus" repeats a letter (4 unique of 5), so it rules out fewer options as an opening guess. Its 2 vowels balance the consonants.

🔤

Scrabble

"Lupus" is worth 7 points before board bonuses. Aim its letters at double/triple-letter and word squares to lift the score.

Words Related to Lupus

Words one letter different

Change a single letter of “lupus” to make these 5-letter words — useful for Wordle and crossword clues.

Words you can make from Lupus

Shorter words formed from the letters in “lupus”.

Explore Similar Words

Try These Tools

Dictionary References

Look up lupus in an authoritative dictionary for full definitions, pronunciation, and etymology.

Word Challenge

Ready to test your word skills?

Download Word Challenge for unlimited word puzzles, a fresh Daily Challenge, and head-to-head multiplayer. Guess the hidden word in six tries or fewer!

Download Free